We are developing new therapeutic agents to treat various cancers such as lung cancer, colorectal cancer, and stomach cancer by analyzing extracellular vesicles secreted by microbe. And Based on the scientific evidence that the microbial extracellular vesicles are connected to the brain through the extracellular vesicles, and the fact that ir regulates our body's metabolic function, we are developing a treatment for diseases such as Alzheimer's dementia, autism, depression and metabolic diseases.

The microbial extracellular vesicle is a lipid bilayer membrane that packs proteins and various metabolites to selectively transfer substances to specific cells in a specific area. And proteins and metabolites contained in extracellular vesicles are transmitted to organelles within the cell, regulating metabolism and immune function to play a key role in cell homeostasis. Microbial extracellular vesicles have the advantage of being easily administered in oral or inhaled form, unlike exosomes and proteins, and can be easily mass-produced. In addition, unlike existing probiotics and products that use live bacteria, microbial extracellular vesicles do not multiply in our body, so side effects that occur in people with reduced immunity when living bacteria are administered can be avoided.

We have reported several studies showing that extracellular vesicles (EVs) secreted by pathogenic bacteria present in the environment are important factors in the pathogenesis of refractory diseases with immune function disorders such as respiratory diseases, cancer, skin diseases, and metabolic diseases. EVs secreted by beneficial bacteria that coexist with us are absorbed and distributed throughout our body and improve immunological homeostasis, which was first identified by suppressing disease outbreaks.